Is there a generic for Desoximetasone?

Yes. The FDA Orange Book lists 34 approved generic (ANDA) applications for Desoximetasone, referencing the brand TOPICORT. Generics rated with an "A" therapeutic-equivalence code are considered substitutable for the brand.

What is the reference-listed drug for Desoximetasone?

TOPICORT (NDA 204141, SUN PHARMA CANADA) is the reference-listed drug, the approved product a generic applicant must show its version is the same as.

What patents protect Desoximetasone?

The Orange Book lists 2 patents against Desoximetasone products, with the earliest listed expiry in 2026. Listed patents cover the drug substance, drug product, or approved methods of use, and a generic launching before they expire must file a Paragraph IV certification.

What dosage forms of Desoximetasone are approved?

Desoximetasone is approved in the following dosage forms: cream, gel, ointment, spray.

FDA Orange Book · active-ingredient family

Desoximetasone

Desoximetasone: 6 brands, 34 generics; first approved Mar 29, 1982; generic available.

Generic availableHas discontinued products

Generic status & protection

Generic available: 34 ANDA applications approved.

Earliest patent expiry May 26, 2026

Brands (NDA)

Generics (ANDA)

Listed patents

Next patent expiry

May 26, 2026

3 mo ago

Brand (NDA) products

Originator applications

TOPICORTRLDRS
SUN PHARMA CANADANDA 2041412013
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% SPRAY TOPICAL Rx AT
TOPICORTRLDRS
TARONDA 0185941985
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% OINTMENT TOPICAL Rx AB
TOPICORTRLD
TARONDA 0187631983
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Discontinued —
TOPICORTRLD
TARONDA 0185861982
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% GEL TOPICAL Discontinued —
TOPICORTRLD
TARONDA 017856—
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% CREAM TOPICAL Discontinued —
TOPICORT LPRLD
TARONDA 018309—
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% CREAM TOPICAL Discontinued —

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	SPRAY	TOPICAL	Rx	AT

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Discontinued	—

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	GEL	TOPICAL	Discontinued	—

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	CREAM	TOPICAL	Discontinued	—

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	CREAM	TOPICAL	Discontinued	—

Generic (ANDA) products (34)

Abbreviated applications

DESOXIMETASONE
COSETTE PHARMS NCANDA 2095952020
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% CREAM TOPICAL Discontinued —
DESOXIMETASONE
RISINGANDA 2109802018
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% CREAM TOPICAL Rx AB
DESOXIMETASONE
THE J MOLNERANDA 2099732018
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% OINTMENT TOPICAL Rx AB
DESOXIMETASONE
ZYDUS LIFESCIENCESANDA 2056202018
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% CREAM TOPICAL Rx AB
DESOXIMETASONE
RISINGANDA 2055942018
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% CREAM TOPICAL Rx AB
DESOXIMETASONE
LUPINANDA 2081242018
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% SPRAY TOPICAL Rx AT
DESOXIMETASONERS
ZYDUS LIFESCIENCESANDA 2052062017
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Rx AB
DESOXIMETASONE
PADAGIS ISRAELANDA 2064412017
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% SPRAY TOPICAL Rx AT
DESOXIMETASONE
LUPINANDA 2081632017
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% CREAM TOPICAL Rx AB
DESOXIMETASONE
LUPINANDA 2081642017
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% CREAM TOPICAL Rx AB
DESOXIMETASONE
SCIEGEN PHARMSANDA 2037872017
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% CREAM TOPICAL Rx AB
DESOXIMETASONE
COSETTE PHARMS NCANDA 2067402016
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Discontinued —
DESOXIMETASONE
LUPINANDA 2080442016
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% OINTMENT TOPICAL Rx AB
DESOXIMETASONE
LUPINANDA 2081042016
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Rx AB
DESOXIMETASONE
RISINGANDA 2042722016
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Rx AB
DESOXIMETASONE
ACTAVIS MID ATLANTICANDA 2049652016
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Rx AB
DESOXIMETASONE
RISINGANDA 2046752016
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% GEL TOPICAL Rx AB
DESOXIMETASONE
NOVEL LABS INCANDA 2067922016
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Rx AB
DESOXIMETASONE
ENCUBEANDA 2081012016
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Discontinued —
DESOXIMETASONE
ACTAVIS MID ATLANTICANDA 2050822015
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% CREAM TOPICAL Rx AB
DESOXIMETASONE
SCIEGEN PHARMSANDA 2032342015
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% CREAM TOPICAL Rx AB
DESOXIMETASONE
PADAGIS ISRAELANDA 0777702015
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Rx AB
DESOXIMETASONE
EPIC PHARMA LLCANDA 2010052014
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Rx AB
DESOXIMETASONE
GLENMARK PHARMS LTDANDA 2028382013
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Discontinued —
DESOXIMETASONE
FOUGERA PHARMSANDA 0786572012
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Rx AB
DESOXIMETASONE
EPIC PHARMA LLCANDA 0907272011
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% GEL TOPICAL Rx AB
DESOXIMETASONE
FOUGERA PHARMSANDA 0783692010
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% CREAM TOPICAL Rx AB
DESOXIMETASONE
PADAGIS USANDA 0775522006
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% GEL TOPICAL Discontinued —
DESOXIMETASONE
PADAGIS ISRAELANDA 0765102003
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% CREAM TOPICAL Rx AB
TOPICORTRS
TAROANDA 0749041998
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% GEL TOPICAL Rx AB
DESOXIMETASONE
ALTANAANDA 0734401998
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Discontinued —
TOPICORT
TAROANDA 0742861996
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% OINTMENT TOPICAL Discontinued —
TOPICORTRS
TAROANDA 0732101990
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.05% CREAM TOPICAL Rx AB
TOPICORTRS
TAROANDA 0731931990
Approved strengths under this FDA application.
Strength Dosage form Route Status TE
0.25% CREAM TOPICAL Rx AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	CREAM	TOPICAL	Discontinued	—

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	SPRAY	TOPICAL	Rx	AT

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	SPRAY	TOPICAL	Rx	AT

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Discontinued	—

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	GEL	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Discontinued	—

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Discontinued	—

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	GEL	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	GEL	TOPICAL	Discontinued	—

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	GEL	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Discontinued	—

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	OINTMENT	TOPICAL	Discontinued	—

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.05%	CREAM	TOPICAL	Rx	AB

Approved strengths under this FDA application.
Strength	Dosage form	Route	Status	TE
0.25%	CREAM	TOPICAL	Rx	AB

Patent & exclusivity timeline

Protection horizon

Patent expiryExclusivity endToday

Listed patents

Orange Book patent file

Patents listed in the FDA Orange Book for this product, with expiration date and patent type.
Patent	Expires	In	Type
8715624	May 26, 2026	3 mo ago	ProductU-1408
8277780	Sep 01, 2028	in 2 yr 1 mo	ProductU-1408

Approval history

FDA approval span

First approval

Mar 29, 1982

45 yr 1 mo ago

Most recent approval

Mar 04, 2020

6 yr 7 mo ago

Approvals span 1982–2020 across 40 FDA applications.

Brand (NDA) 615%

Generic (ANDA) 3485%

Desoximetasone: frequently asked questions

Generics, reference-listed drug, patents, and exclusivity for this active ingredient, from the FDA Orange Book.

Built directly from the FDA Orange Book data file (products, patents, and exclusivity). TE codes, RLD/RS flags, patent expirations, and exclusivity dates match the official FDA record. Listed patents reflect those the NDA holder submits under 21 U.S.C. 355 and are not exhaustive.

Related FDA reference tools

Your Next Submission Could Take 6+ Fewer Weeks and Cost $250K Less.

Book a Demo