FDA Orange Book · active-ingredient family
Metoprolol succinate
Metoprolol succinate: 2 brands, 28 generics; first approved Jan 10, 1992; generic available.
Generic availableHas discontinued products
Generic status & protection
Generic available: 28 ANDA applications approved.
Earliest patent expiry
Brands (NDA)
2
Generics (ANDA)
28
Listed patents
2
Next patent expiry
Jul 09, 2035
in 8 yr 11 mo
Brand (NDA) products
Originator applications
- SPILNDA 21042820184 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE CAPSULE, EXTENDED RELEASE ORAL Rx — EQ 50MG TARTRATE CAPSULE, EXTENDED RELEASE ORAL Rx — EQ 100MG TARTRATE CAPSULE, EXTENDED RELEASE ORAL Rx — EQ 200MG TARTRATE CAPSULE, EXTENDED RELEASE ORAL Rx — - TOPROL-XLRLDMELINTA THERAPNDA 01996220014 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB
Generic (ANDA) products (28)
Abbreviated applications
- METOPROLOL SUCCINATEZHEJIANG JUTAI PHARMANDA 21411020264 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEIPCA LABS LTDANDA 20698020254 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATESUNSHINEANDA 21400420244 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATELUPINANDA 20927220234 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — - METOPROLOL SUCCINATEGRANULESANDA 21650920234 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — - METOPROLOL SUCCINATEGRANULESANDA 21691620234 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEACCORD HLTHCAREANDA 21563720224 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — - METOPROLOL SUCCINATEYICHANG HUMANWELLANDA 21385420224 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEPRINSTON INCANDA 21059720222 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — - METOPROLOL SUCCINATEALKEM LABS LTDANDA 21114320204 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEHETERO LABS LTD IIIANDA 20554120204 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEPHARMADAXANDA 20302820202 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEPHARMADAXANDA 20369920202 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEVISUM PHARMANDA 20720620184 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATECIPLAANDA 20746520183 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEZYDUS PHARMSANDA 20389420184 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATENOVAST LABSANDA 20410620184 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEACTAVIS ELIZABETHANDA 20416120164 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEREDDYSANDA 07888920122 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEDR REDDYS LABS LTDANDA 09061720122 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEMYLAN PHARMS INCANDA 20203320114 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — - METOPROLOL SUCCINATEWOCKHARDT BIO AGANDA 09061520104 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB - METOPROLOL SUCCINATEACTAVIS LABS FL INCANDA 07729820102 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — - METOPROLOL SUCCINATEACTAVIS LABS FL INCANDA 07686220092 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Rx AB EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — - METOPROLOL SUCCINATENESHER PHARMSANDA 0771762008
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — - METOPROLOL SUCCINATENESHER PHARMSANDA 0777792008
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — - METOPROLOL SUCCINATENESHER PHARMSANDA 07664020072 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — - METOPROLOL SUCCINATESANDOZANDA 07696920064 strengths
Approved strengths under this FDA application. Strength Dosage form Route Status TE EQ 25MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 50MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 100MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued — EQ 200MG TARTRATE TABLET, EXTENDED RELEASE ORAL Discontinued —
Patent & exclusivity timeline
Protection horizon
Patent expiryExclusivity endToday
Listed patents
Orange Book patent file
| Patent | Expires | In | Type |
|---|---|---|---|
| 9504655 | in 8 yr 11 mo | Product | |
| 9700530 | in 8 yr 11 mo | Product |
Approval history
FDA approval span
First approval
35 yr 3 mo ago
Most recent approval
5 mo ago
Approvals span 1992–2026 across 30 FDA applications.
Brand (NDA) 27%
Generic (ANDA) 2893%
Metoprolol succinate: frequently asked questions
Generics, reference-listed drug, patents, and exclusivity for this active ingredient, from the FDA Orange Book.
Built directly from the FDA Orange Book data file (products, patents, and exclusivity). TE codes, RLD/RS flags, patent expirations, and exclusivity dates match the official FDA record. Listed patents reflect those the NDA holder submits under 21 U.S.C. 355 and are not exhaustive.
Related FDA reference tools
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- 510(k) Predicate DatabaseSearch FDA 510(k) clearances and map predicate-device lineage.
- FDA 483 DatabaseFDA Form 483 observations and inspection records by firm, date, and citation.
