Orange Book product · Brand (NDA)
YUVEZZI
BRIMONIDINE TARTRATE; CARBACHOL
At a glance
Jan 28, 2026
Approved
Brand (NDA)
Application
Not listed
TE code
6
Listed patents
Key dates
Approval
FDA approval date of this drug product.
Jan 28, 2026
5 mo ago
Today
Exclusivity ends · NP
New product exclusivity (3 years)
Jan 28, 2029
in 2 yr 8 mo
Patent 8455494 expires
Listed method-of-use patent (U-3741) expiration.
May 24, 2030
in 4 yr
Patent 8455494 expires
Listed method-of-use patent (U-4419) expiration.
May 24, 2030
in 4 yr
Patent 8455494 expires
Listed method-of-use patent (U-4420) expiration.
May 24, 2030
in 4 yr
Patent 12268662 expires
Listed drug product patent expiration.
Nov 10, 2042
in 16 yr 8 mo
Patent 12268662 expires
Listed drug product patent expiration.
Nov 10, 2042
in 16 yr 8 mo
Patent 12268662 expires
Listed drug product patent expiration.
Nov 10, 2042
in 16 yr 8 mo
Pharmaceutical detail
Active ingredient
BRIMONIDINE TARTRATE; CARBACHOL
Strength
0.1%;2.75%
Dosage form
SOLUTION/DROPS
Route
OPHTHALMIC
TE code
Not listed
Application
NDA 220142
Product number
001
Marketing status
RX
Reference listed drug (RLD)
Yes
Reference standard (RS)
Yes
Active-ingredient family
View full familyThis is a reference-listed drug (RLD) — the basis for generic (ANDA) applications. Other products sharing this ingredient are listed below.
Marketing exclusivity (1)
- NPNew product exclusivity (3 years)
Jan 28, 2029
in 2 yr 8 mo
Listed patents (6)
| Patent | Expires | In | Type |
|---|---|---|---|
| 8455494 | May 24, 2030 | in 4 yr | U-3741 |
| 8455494 | May 24, 2030 | in 4 yr | U-4419 |
| 8455494 | May 24, 2030 | in 4 yr | U-4420 |
| 12268662 | Nov 10, 2042 | in 16 yr 8 mo | ProductU-3741 |
| 12268662 | Nov 10, 2042 | in 16 yr 8 mo | ProductU-4419 |
| 12268662 | Nov 10, 2042 | in 16 yr 8 mo | ProductU-4420 |
